|
KMID : 0357920130470040383
|
|
Korean Journal of Pathology
2013 Volume.47 No. 4 p.383 ~ p.387
|
|
|
Sebaceous Carcinoma Arising in Mature Cystic Teratoma of Ovary
|
|
An Hyo-Jeong
Jung Yong-Han
Yoon Hye-Kyoung
Jung Soo-Jin
|
|
|
Abstract
|
|
|
|
Roughly 1% of mature cystic teratomas undergo malignant transformation. In particular, cutaneous- type adnexal neoplasms may occur in mature cystic teratomas. Sebaceous carcinomas, which arise from mature cystic teratomas, have rarely been observed, with only seven cases previously reported. Here, we present a case of a 69-year-old female who had pelvic pain for two weeks and who subsequently underwent bilateral salpingo-oophorectomy and hysterectomy. Her left ovary showed a unilocular cyst, measuring 22.0 cm in diameter, filled with sebaceous material and a few hairs. A luminally-protruding solid mass measuring 4.0 cm in diameter was also noted. Microscopic findings revealed lobular or diffusely arranged basophilic, atypical sebaceous cells connected to a typical mature cystic teratoma. Tumor cells demonstrated positive immunoreactivity for high molecular weight cytokeratin, cytokeratin 7, cytokeratin 19, epithelial membrane antigen, and carcinoembryonic antigen. Here, we present a case of sebaceous carcinoma arising from a mature cystic teratoma along with a review of previously published reports.
|
|
|
KEYWORD
|
|
|
Sebaceous carcinoma, Sebaceous adenoma, Mature cystic teratoma, Ovary
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
  
|
|